Strong evidence.

The CPT® cold plasma adjunctive therapy solution has been proven effective.

What is the current state of research and evidence regarding cold plasma?

Scientifically researched and professionally evaluated

Extensive research demonstrates the effectiveness of cold plasma.
Leading professional associations also confirm its clinical relevance.

In its latestposition paper , the European Wound Management Association (EWMA) has systematically reviewedinternational studies, clinical data, and other scientific evidence regarding the use of cold plasma.

Cold plasma can
reduce the bacterial load on the
wound—including
multidrug-resistant
pathogens—reliably
.²

Cold plasma can
stimulate
cell regeneration
and tissue repair
.2

Cold plasma can
limit infections and prevent further
spread.²

Cold plasma is
used
perceived
and
and is generally
well tolerated.²

Cold plasma can therefore help heal wounds that are difficult to heal.²

Current evidence on large-area CPT® cold plasma therapy

Power Study

The largest ongoing study to date on large-area CPT® cold plasma (POWER) is being conducted in collaboration with the German Society for Wound Healing and is the first IQWiG-compliant (here is the link; please link only the word: https://www.iq-
wig.de/) study on cold plasma that meets these requirements.

The interim results show that CPT® cold plasma therapy is significantly more effective than standard wound therapy (SWT) for chronic lower-leg wounds:

Accelerated wound healing

Compared to the SWT group, the wound closure factor in the CPT group increased significantly to 214%. This indicates that wounds heal significantly faster with CPT® treatment.³

Pain relief

Patients in the CPT group reported less wound pain and a reduction in passive pain to 0 (median) was observed.³

Improving quality of life

In patients in the CPT group, a significant and clinically meaningful improvement in quality of life was observed.³

Reduced need for antibiotics

The CPT group required only 4% of antibiotics, compared with 23% in the SWT group.³

Accelerated wound healing

Compared to the SWT group, the wound closure factor in the CPT group increased significantly to 214%.
This indicates that wounds heal significantly faster with CPT® treatment.³

Pain relief

Patients in the CPT group reported less wound pain, and a reduction in passive pain to 0 (median) was recorded.³

Improving quality of life

In patients in the CPT group, a marked and clinically significant improvement in quality of life was observed.
³

Reduced need for antibiotics

The CPT group required antibiotics in only 4% of cases, compared with 23% in the SWT group.³

Other publications

Additional clinical publications on large-area CPT® cold plasma:

#chronic wounds #vasculitis #lymphedema #post-thrombotic syndrome #diabetes mellitus

"Cold plasma therapy for
various types of wounds:
Results of a pilot study."
Abu Rached et al. (2025),
Current Dermatology

For publication

#Multi-drug-resistant colonized burns #Large-area cold plasma therapy #dermal skin substitute #skin transplantation #skin substitutes

"The Successful Treatment
of Multi-Resistant Colonized
Burns with Large-Area Cold
Plasma Therapy and Dermis
Substitute Matrix–A Case Report."
Milewski et al. (2024), *
* *European Burn Journal*

For publication

#Chronic non-healing wound #Complete healing in 8 weeks #Non-invasive therapy #No adverse effects